Publications

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. CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer.. In Cancer Cell., 2020.

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. Integrative and perturbation based analysis of the transcriptional dynamics of TGFβ/BMP system components in transition from embryonic stem cells to neural progenitors.. In Stem Cells., 2019.

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. BORIS promotes chromatin regulatory interactions in treatment-resistant cancer cells.. In Nature., 2019.

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. Giotto, a pipeline for integrative analysis and visualization of single-cell spatial transcriptomic data.. In BioRxiv., 2019.

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. RESCUE: imputing dropout events in single- cell RNA-sequencing data.. In BMC Bioinformatics., 2019.

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. CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation.. In Nature Communications., 2019.

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. Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH+. In Nature., 2019.

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. NK cells mediate synergistic antitumor effects of combined inhibition of HDAC6 and BET in a SCLC preclinical model.. In Cancer Research., 2018.

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. Genomic and functional fidelity of small cell lung cancer patient-derived xenografts.. In Cancer Discovery., 2018.

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. Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade.. In Journal Thorac Oncol., 2017.

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. Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non-Small Cell Lung Cancer.. In Cancer Discov., 2017.

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. Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells.. In Stem Cells., 2017.

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. Multiparametric profiling of non-small-cell lung cancers reveals distinct immunophenotypes.. In JCI Insight., 2016.

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. BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells.. In Stem Cell Reports., 2016.

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. CDK4/6 Inhibition Augments Anti-Tumor Immunity by Enhancing T Cell Activation.. In Cancer Discovery., 2013.

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. Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1.. In Neuron., 2013.

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. Few Smad proteins and many Smad-interacting proteins yield multiple functions and action modes in TGFβ/BMP signaling in vivo.. In Cytokine Growth Factor Rev., 2011.

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